Whether it's prescription Retin-A or any number of over the counter acne care treatments containing retinol, the biggest effect of this treatment is it's ability to irritate the skin and cause flaking. For this reason many people give up on Retin-A before it has a chance to work. To help avoid some of the skin irritation that is common with this treatment, it is best to use a good quality moisturizer throughout the day. If skin flaking occurs, use a wash cloth to remove the flaking and reapply some moisturizer.
Generally, the dead cells inside the follicle tend to shed slowly and expelled on the surface of the skin. However, in patients who have overactive sebaceous glands, these cells tend to shed more rapidly.
The production of sebum increases in line with the generation of certain hormones. During the menstrual cycle, the production of androgens in women increases at certain times. The activity of these androgens (e.g. testosterone) is believed to be responsible for acne, so if their production could be reduced, then the incidence of acne should be likewise reduced. Androgens promote acne by increasing the rate of production of oily sebum by the sebaceous glands in the skin. This gives some women a natural healthy glow, while others are provided with a sticky oil slick that mixes with dead skin cells to block up skin pores.
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